[ 1 ]Zonated mechanosensing by PIEZO1 controls liver regeneration

[ 2 ]Leucine-tRNA-synthetase-2-expressing B cells contribute to colorectal cancer immunoevasion

[ 3 ]N6-methyladenosine-modified TRAF1 promotes sunitinib resistance by regulating apoptosis and angiogenesis in a METTL14-dependent manner in renal cell carcinoma

[ 4 ]Disrupting KAT8 Liquid–Liquid Phase Separation with Hybrid Vesicle–Liposome Platform for Enhanced PD-L1 Blockade Treatment

[ 5 ]Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity

[ 6 ]Zinc accumulation-induced integrated stress response triggers β-cell identity loss

[ 7 ]Macrophage IRX3 promotes diet-induced obesity and metabolic inflammation

[ 8 ]Cancer-associated fibroblasts suppress ferroptosis and induce gemcitabine resistance in pancreatic cancer cells by secreting exosome-derived ACSL4-targeting miRNAs

[ 9 ]Hepatic GPR110 contributes to sex disparity in the development of MASH through oestrogen receptor α-dependent signalling

[ 10 ]Perturb-seq uncovers pathological obstacles to direct cardiac reprogramming in vivo

[ 11 ]Exosomes from young healthy human plasma promote functional recovery from intracerebral hemorrhage via counteracting ferroptotic injury

[ 12 ]Bacteroides fragilis toxin promotes gall bladder cancer in mice

[ 13 ]Microglial CD31 suppresses Aβ clearance and promotes Alzheimer pathology in 5×FAD mice

[ 14 ]A molecular framework of the Rht-A1–TaLA1-D module controlling tiller angle in wheat

[ 15 ]MARCH2 prevents doxorubicin-induced cardiomyopathy by stabilizing NR1H2 and promoting clearance of apoptotic cardiomyocytes

[ 16 ]Structural insights into C-terminus-mediated RNA target cleavage by a mesophilic prokaryotic argonaute

[ 17 ]Multiomics analysis of the molecular and single-cell responses of rice after deep-space flight on Chang’e-5

[ 18 ]Blocking the m6Am methyltransferase PCIF1 releases STAT1-mediated Th1 immunity to potentiate cancer immunotherapy

[ 19 ]Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency

[ 20 ]Rational Development of Hypervalent Glycan Shield-Binding Nanoparticles with Broad-Spectrum Inhibition against Fatal Viruses Including SARS-CoV-2 Variants

[ 21 ]CsZAT6/12 response auxin signaling to differentially regulate theanine-dominated nitrogen flow in tea roots (Camellia sinensis)

[ 22 ]ICAM1 mRNA entraps ILF2/ILF3 to inhibit transcription of EIF4E and global protein synthesis

[ 23 ]H2O2 sulfenylates GRF8 to facilitate jasmonate signaling by relieving MYC2 inhibition in Arabidopsis

[ 24 ]Chemoproteomic profiling reveals histone H4 dopaminylation inhibiting cell growth

[ 25 ]A rice ceRNA module suppresses Rhizoctonia solani–induced cross-kingdom RNAi to reduce fungal pathogenicity

[ 26 ]The insect Toll pathway activates antibacterial immunity against the citrus Huanglongbing pathogen

[ 27 ]TET1 as a master regulator controlling GPX4-dependent and -independent ferroptosis surveillance in acute myeloid leukemia

[ 28 ]Modulation of PKCα/ETS1 by klotho restores CYB5R4-dependent mitochondrial function in proximal tubular epithelial cells to attenuate the progression of diabetic kidney disease

[ 29 ]EGFR orchestrates neutrophil activation and NETosis via CEBPβ-dependent PGLYRP1 induction

[ 30 ]Ginseng-derived vesicle-like nanoparticles deliver pgi-MIR6136a-p3 for sepsis therapy via ELF3/NF-κB signaling axis

[ 31 ]Targeting the HIF-1α/PPARγ axis with curcumin carbon dots to combat uranium nephrotoxicity

[ 32 ]FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

[ 33 ]Interrogating glioma-M2 macrophage interactions identifies Gal-9/Tim-3 as a viable target against PTEN-null glioblastoma

[ 34 ]Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset

[ 35 ]Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1α/NF-κB feedback pathway to inhibit liver fibrosis

[ 36 ]Effects of ZmHIPP on lead tolerance in maize seedlings: Novel ideas for soil bioremediation

[ 37 ]The BnTFL1-BnJAM3-BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus

[ 38 ]EGR Proteins Mediate Interferon-Independent Anti-HSV-1 Responses Through Viral and Host Targets

[ 39 ]ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α-PADI4 Pathway to Initiate Bone Aging

[ 40 ]Maize Anther Development Involves Translated Open Reading Frames From 3′ Untranslated Regions

[ 41 ]SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis

[ 42 ]Cancer Cell-Intrinsic Cholesterol Induces Lipid-Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

[ 43 ]SIRT6-Mediated Deacetylation of ATF3 Promotes Silica-Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

[ 44 ]ANXA2-mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

[ 45 ]Renal Tubular Epithelial CRLF1 Interacts With ITGB1 to Accelerate Fibrosis During the Transition From AKI to CKD

[ 46 ]OsFTL1 integrates circadian and photoperiodic signals to optimize flowering time for ecological adaptation in rice

[ 47 ]The long non-coding RNA NEXUS arose from a chromosomal structural variation enhances drought tolerance through epigenetic regulation in allotetraploid cotton

[ 48 ]Rice roots recruit Bacillus via the secretion of heptadecanoic acid

[ 49 ]Single-cell chromatin accessibility and cis-regulatory element analyses in plants using the scPlantReg platform

[ 50 ]Sulfenylation of ENOLASE2 facilitates H2O2-conferred freezing tolerance in Arabidopsis

[ 51 ]Glucosylceramide regulates depression through activating peroxisome proliferator-activated receptor gamma in dorsal striatum

[ 52 ]CmERF5-CmRAP2.3 transcriptional cascade positively regulates waterlogging tolerance in Chrysanthemum morifolium

[ 53 ]A novel miR167a-OsARF6-OsAUX3 module regulates grain length and weight in rice

[ 54 ]A transcription factor STOP1-centered pathway coordinates ammonium and phosphate acquisition in Arabidopsis

[ 55 ]Argonaute-mediated RNA editing selectively repairs point mutations

[ 56 ]RPRD1A drives lenvatinib resistance in hepatocellular carcinoma via the ITGA5-FAK signaling axis

[ 57 ]UBTF–HSP90A–MIF stress circuit drives lenvatinib resistance and immune exclusion in hepatocellular carcinoma

[ 58 ]Genetically engineered extracellular vesicles-based collagen-targeting bioinspired scaffold for tendon regenerative repair

[ 59 ]The asymmetrical ROS–METTL3–ESR1 axis in paraspinal muscle progenitor cells determines the progression of adolescent idiopathic scoliosis

[ 60 ]COL1A1-induced LOXL2 promotes ovarian cancer metastasis via a feedback loop upon inhibiting EGFR lysosomal degradation

[ 61 ]SNRPC promotes chemoresistance in Wilms tumor via the NF-κB-CXCL17 axis regulating M2-Type TAMs infiltration and targeted nanotherapy research

[ 62 ]HOXA10 drives immune evasion in early lung adenocarcinoma by recruiting immunosuppressive macrophages via NF-κB/CCL2 signaling

[ 63 ]Targeted Inhibition of P. gingivalis OMV-derived TsRNA by tetrahedral framework nucleic acids promotes periodontal regeneration

[ 64 ]A cytochrome P450 gene, GmSUR2a, confers submergence tolerance and improves yield in soybean by modulating auxin homeostasis

[ 65 ]A translatome-transcriptome multi-omics gene regulatory network reveals the complicated functional landscape of maize

[ 66 ]YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis

[ 67 ]NRF1 predominantly causes EZH2 overexpression in cancer cells

[ 68 ]Methylation of a MITE insertion in the MdRFNR1-1 promoter is positively associated with its allelic expression in apple in response to drought stress

[ 69 ]The transcriptional repressors VAL1 and VAL2 mediate genome-wide recruitment of the CHD3 chromatin remodeler PICKLE in Arabidopsis

[ 70 ]Cytokinin-responsive MdTCP17 interacts with MdWOX11 to repress adventitious root primordium formation in apple rootstocks

[ 71 ]Melatonin may suppress lung adenocarcinoma progression via regulation of the circular noncoding RNA hsa_circ_0017109/miR-135b-3p/TOX3 axis

[ 72 ]Unveiling a novel function of Aconitase-2: attenuating lung ischemia-reperfusion injury via inhibition of pulmonary endothelial apoptosis

[ 73 ]WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling

[ 74 ]GPI promotes immunosuppression in anaplastic thyroid carcinoma via O-GlcNAcylated THBS1-mediated myeloid cell crosstalk

[ 75 ]CRL4AMBRA1-mediated progesterone receptor degradation drives progestin resistance and represents a therapeutic vulnerability in endometrial cancer

[ 76 ]A phased small interfering RNA acts in an OsAGO2-dependent manner to mediate OsARF7 cleavage and promote male fertility in rice

[ 77 ]The OsGSK1-OsBZR3-OsJAZ4 module integrates nitrate signaling with brassinosteroid and jasmonic acid crosstalk to drive cell wall remodeling for salt recovery in rice

[ 78 ]Natural variations in GhNF-YB3 contribute to seed cotton yield by modulating source-to-sink sucrose allocation

[ 79 ]Heterodimers of the MADS transcription factors GhAGL1 and GhAGL4 modulate cotton fiber initiation and elongation

[ 80 ]KIN10-mediated phosphorylation attenuates cooperative repression of oil accumulation by AHL14 and AHL29 in Arabidopsis seeds

[ 81 ]The CdFBX1-CdMYB26-CdMYB5 module regulates ion homeostasis under salt stress by fine-tuning CdSOS1 expression in bermudagrass

[ 82 ]Rhizobial auxin activates transcription factors to orchestrate YUC2-dependent auxin biosynthesis for soybean nodule development

[ 83 ]Mechanistic Insights Into NFIX‐Mediated DNA Recognition and Transcriptional Regulation in Skeletal Muscle

[ 84 ]Cellular senescence in hepatocellular carcinoma induced by a long non-coding RNA-encoded peptide PINT87aa by blocking FOXM1-mediated PHB2

[ 85 ]LARP6 suppresses colorectal cancer progression through ZNF267/SGMS2-mediated imbalance of sphingomyelin synthesis

[ 86 ]The AGPS regulatory variant rs113671272 confers esophageal squamous cell carcinoma susceptibility through allele-specific MEIS3 binding and NF-κB activation in Chinese populations

[ 87 ]LINC00473-modified bone marrow mesenchymal stem cells incorporated thermosensitive PLGA hydrogel transplantation for steroid-induced osteonecrosis of femoral head: A detailed mechanistic study and validity evaluation

[ 88 ]Sphingosine‐1‐Phosphate Receptor 3 Confers Tumor Metastasis in Lung Cancer Resistant to Third‐Generation EGFR Inhibitor

[ 89 ]Hypoxic Reprogramming of ACOX1-Driven HSP90AB1 Crotonylation Stabilizes Thioredoxin to Orchestrate Redox Homeostasis in Oral Squamous Cell Carcinoma

[ 90 ]Circular RNA circERBB2 promotes gallbladder cancer progression by regulating PA2G4-dependent rDNA transcription

[ 91 ]Hyaluronic acid-CD44 signaling defines therapeutic resistance and immunosuppressive microenvironment in peritoneal metastasis of gastric cancer

[ 92 ]Stress Granule-Associated ZmCTU2 Confers Thermotolerance in Maize via Coordinated Regulation of Proteostasis and ROS Homeostasis

[ 93 ]The miR167-OsARF12 module regulates rice grain filling and grain size downstream of miR159

[ 94 ]The MdICE1/MdFAMA-MdTYDC Transcriptional Module Confers Cold Tolerance by Regulating Dopamine Metabolism in Apple

[ 95 ]MdRLKT1–MdRAX2–MdMKS1 Module Positively Regulating Resistance to Cytospora mali in Apple

[ 96 ]Regulatory Mechanism of CsMYB1-CsMYB82/CsbHLH48‑CsCAD4 Model for Resistance Against Colletotrichum gloeosporioides in Camellia sinensis

[ 97 ]α-Hederin inhibits the platelet activating factor-induced metastasis of HCC cells through disruption of PAF/PTAFR axis cascaded STAT3/MMP-2 expression

[ 98 ]Fusobacterium nucleatum promotes colorectal cancer metastasis through miR-1322/CCL20 axis and M2 polarization

[ 99 ]NK-cell-derived exosomes exert antitumor potency via miR-140/XYLT1/HSPG2 axis

[ 100 ]Anti-CHAC1 exosomes for nose-to-brain delivery of miR-760-3p in cerebral ischemia/reperfusion injury mice inhibiting neuron ferroptosis