[ 1 ]GL-V9 disrupts the mitochondrial homeostasis and triggers the integrated stress response by promoting the binding of cytosolic MDM2 with NDUFS1 in colorectal cancer

[ 2 ]ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation

[ 3 ]NQO1-Mediated Anoikis Resistance and Immune Evasion Define a High-Risk Multi-Omic Subtype for Precision Management of T1 High-Grade Bladder Cancer

[ 4 ]Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

[ 5 ]Exosomal circZNF451 restrains anti-PD1 treatment in lung adenocarcinoma via polarizing macrophages by complexing with TRIM56 and FXR1

[ 6 ]CRMP2 inhibits metastasis formation by impairing ILF3-dependent stabilization of CXCL10 mRNA in breast cancer

[ 7 ]Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218

[ 8 ]TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG

[ 9 ]Targeting lysosomal HSP70 induces acid sphingomyelinase-mediated disturbance of lipid metabolism and leads to cell death in T cell malignancies

[ 10 ]The flavonoid GL-V9 alleviates liver fibrosis by triggering senescence by regulating the transcription factor GATA4 in activated hepatic stellate cells

[ 11 ]Inhibition of androgen receptor enhanced the anticancer effects of everolimus through targeting glucose transporter 12

[ 12 ]FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation

[ 13 ]The flavonoid GL-V9 induces oxidative stress mediated apoptosis in small cell lung cancer by promoting STEAP3 degradation

[ 14 ]DLAT Sustains Redox Homeostasis and Prevent Colorectal Cancer from Ferroptosis by Regulating SLC25A39-Mediated Mitochondrial Glutathione Transport

[ 15 ]Macrophage glycine transporter supports IL-1β production by modulating the AKT1/mTOR/NLRP3 pathway

[ 16 ]One-Two Punch Therapy for the Treatment of T-Cell Malignancies Involving p53-Dependent Cellular Senescence

[ 17 ]Knockdown of PGM1 enhances anticancer effects of orlistat in gastric cancer under glucose deprivation

[ 18 ]Pharmacologic targeting of the P-TEFb complex as a therapeutic strategy for chronic myeloid leukemia

[ 19 ]Targeting VCP with V8 suppresses glioblastoma development via formation of aggregates and disruption of mitophagy flux

[ 20 ]Enhanced De Novo Lipid Synthesis Mediated by FASN Induces Chemoresistance in Colorectal Cancer

[ 21 ]AKR1C3 Binds β-Trcp to Promote the Degradation of TFRC to Protect Hepatocellular Carcinoma From Ferroptosis

[ 22 ]PDK4-driven metabolic reprogramming enhances mesothelial cell invasion in colorectal cancer peritoneal metastasis: PDK4 regulates mesothelial cell invasion in colorectal peritoneal metastasis

[ 23 ]PAK3 promotes the metastasis of hepatocellular carcinoma by regulating EMT process

[ 24 ]Metformin Activates AMPK to Restrain Mitochondrial ROS-Driven Necroptosis in Cadmium Neurotoxicity

[ 25 ]Lysosomal membrane permeabilization mediated apoptosis involve in perphenazine-induced hepatotoxicity in vitro and in vivo

[ 26 ]Ubiquitin C-terminal hydrolase L3 promotes liver cancer cell proliferation by modulating the AMP-activated protein kinase signaling pathway

[ 27 ]Inhibition of EMMPRIN by microRNA‑124 suppresses the growth, invasion and tumorigenicity of gliomas

[ 28 ]Targeting WWP1 ameliorates osteoarthritis by suppressing KLF15 ubiquitination to restore mtDNA and mitochondrial function