Gatifloxacin hydrochloride是一种广谱氟喹诺酮类抗生素，通过抑制细菌II型拓扑异构酶及DNA旋转酶发挥抗菌作用，适用于细菌性结膜炎等感染性疾病的研究。
| 英文别名 (English Synonym) | Gatifloxacin hydrochloride |
| 中文名称 (Chinese Name) | 加替沙星盐酸盐 |
| 靶点 (Target) | Topoisomerase |
| 通路 (Pathway) | Cell Cycle/DNA Damage |
| CAS号 (CAS NO.) | 121577-32-0 |
| 分子式 (Formula) | C19H23ClFN3O4 |
| 分子量 (Molecular Weight) | 411.86 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于H2O |
-25~-15℃保存，有效期3年
[1] Yamada C, Nagashima K, Takahashi A, Ueno H, Kawasaki Y, Yamada Y, Seino Y, Inagaki N. Gatifloxacin acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis. Eur J Pharmacol. 2006 Dec 28;553(1-3):67-72. doi: 10.1016/j.ejphar.2006.09.043. Epub 2006 Sep 28. PMID: 17070519.
[2] Daw-Garza A, Welsh O, Said-Fernández S, Lozano-Garza HG, Waksman de Torres N, Rocha NC, Ocampo-Candiani J, Vera-Cabrera L. In vivo therapeutic effect of gatifloxacin on BALB/c mice infected with Nocardia brasiliensis. Antimicrob Agents Chemother. 2008 Apr;52(4):1549-50. doi: 10.1128/AAC.00148-08. Epub 2008 Feb 19. PMID: 18285484; PMCID: PMC2292517.
