Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS.

稀释比 WB:1/500-1/1000; IF:1/50-1/200; IP: 1/20

Western blot

Western blot analysis of PLK1 in Jurkat, C6 lysates using PLK1 antibody.

Immunocytochemistry

Immunocytochemistry analysis of PLK1(green) in HeLa using PLK1 antibody, and DAPI(blue).

-25~-15℃保存