Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

稀释比WB: 1/500-1/1000 IHC: 1/50-1/100

产品数据

	Western blot analysis of Src in SH-SY5Y, U87-MG lysates using Src antibody.
	Western blot analysis of Src in C6, 3T3 lysates using Src antibody.
IHC
	IHC analysis of paraffin-embedded Human colon cancer using Srcantibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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