TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Rhesus Macaque TARC is an 8.1 kDa protein containing 71 amino acid residues, including the four conserved cysteine residues present in CC chemokines.
Product Properties
Synonyms |
Thymus and Activation Regulated Chemokine, CCL17, ABCD-2 |
Accession |
Q8HYP9 |
GeneID |
574180 |
Source |
E.coli-derived Rhesus Macaque TARC protein,Ala24-Ser94. |
Molecular Weight |
Approximately 8.1 kDa. |
AA Sequence |
ARGTNVGREC CLKYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQNKAIC SDPNDKKVKK ALKYLQSLER S |
Tag |
None |
Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity |
> 97% by SDS-PAGE and HPLC analyses. |
Biological Activity |
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/mL. |
Endotoxin |
<0.1 EU/μg of protein as determined by LAL method. |
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, 300 mM NaCl, pH 7.4, with 0.02 % Tween-20. |
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only.
HB220418