May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of Phospho-alpha Synuclein (Ser129) in mouse brain lysates using Phospho-alpha Synuclein (Ser129) antibody.

Immunohistochemistry analysis of paraffin-embedded Human brain using Synuclein (Phospho-Ser129) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.