RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of PTBP2 in mouse testis, Hela, LOVO, HepG2 lysates using PTBP2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human gastric cancer using PTBP2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.