Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;IP:1/50

Western blot analysis of Dkk3 in Human fetal kidney lysates using DKK3 antibody.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.