Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment.

Reactivity:Cyanobacteria

推荐稀释比 WB:1/500-1/1000

Western blot analysis of LexA DNA Binding Region in Recombinant LexA protein lysates using LexA DNA Binding Region antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。