Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of RASSF1 in HeLa lysates using RASSF1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。