Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor.

Western

Western blot analysis of ATR in K562 lysates using ATR antibody

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human ovarian cancer using ATR antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.