Smad4 transcription factor that mediates signal transduction by the transforming growth factor superfamily. The common smad (co-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. Promotes binding of the Smad2/Smad4/Fast-1 complex to DNA and provides an activation function required for Smad1 or Smad2 to stimulate transcription.

推荐稀释比 WB:1/500-1/1000; ICC/IF:1/100; FC:1/200-1/500; IP:1/20-1/50

Immunocytochemistry analysis of Smad4 (green) in Hela using Smad4 antibody,and DAPI(blue).

Western blot analysis of Smad4 in C6, Ramos lysates using Smad4 antibody.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.