The interleukin (IL)-12 family of cytokines, including IL12 and IL 23, play an important role in driving aberrant Th1 and Th17 immune responses in patients with Crohn's disease (CD) . Targeting this pathway has opened new avenues for therapeutic intervention.

高活性、高纯度、低内毒素、高批间一致性

                                        SDS-PAGE

Human IL-23 alpha&IL-12 beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

                                                   HPLC

The purity of Human IL-23 alpha&IL-12 beta is greater than 95% as determined by SEC-HPLC.

                                                   ELISA Data

ELISA Data 1: Immobilized Human IL-23R, hFc Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-23 alpha&IL-12 beta, His Tag with the EC50 of 46.4ng/ml determined by ELISA.

ELISA Data 2: Immobilized Human IL-23 alpha&IL-12 beta, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-IL-23 Antibody, hFc Tag with the EC50 of 3.3 ng/ml determined by ELISA.

-25~-15℃保存，收到货之日起，有效期1年。复溶后， -85~-65℃保存，3个月有效期。避免反复冻融。