Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.

推荐稀释比 IHC:1/100-1/200;IF:1/50-1/200;FC:1/50-1/100

Immunofluorescence analysis of CD3 zeta in K562 cells using CD3 zeta antibody(green). Blue: DRAQ5 fluorescent DNA dye.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.