产品说明书
FAQ
COA
已发表文献
Activin A, a homodimer of activin βA subunits, is a member of the transforming growth factor (TGF)-β super-family. Activin A is produced by the placenta during human pregnancy, has been recognized as a multifunctional cytokine expressed in a wide range of tissues and cells with roles in regulation of wound repair, cell differentiation, apoptosis, embryogenesis, and inflammation.
性能参数
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Synonyms |
Activin A, activin AB alpha polypeptide, inhibin beta A chain |
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Uniprot No. |
P08476 |
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Source |
Human/Murine/Rat Activin A Protein is expressed from CHO cell.It contains Gly311 - Ser426. |
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Molecular Weight |
Apparent molecular mass of 24 kDa in SDS-PAGE under non-reducing conditions, 14 kDa under reducing conditions, a disulfide-linked homodimer of two 116 amino acid glycosylated polypeptide chains. |
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Biological Activity |
Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 0.2-1.2 ng/mL.The specific activity of Activin A is approximately 1 IU/μg. |
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Purity |
> 95% as determined by SDS-PAGE. |
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Endotoxin |
<0.01 EU per 1μg of the protein by the LAL method. |
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Formulation |
Lyophilized from 0.2 μm filtered concentrated solution in 30 % acetonitrile and 0.1 % TFA. |
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Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 4 mM HCl to a concentration of 0.1-0.5 mg/ml. Further dilutions should be made in appropriately buffered solutions. |
储存条件
The product should be stored at -25~-15℃ for 1 year from date of receipt.
1 month, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
注意事项
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
Ver. CN20230424
