Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.

Western

Western blot analysis of Phospho-Tau (S199) in mouse hippocampus lysates using Phospho-Tau (Ser199) antibody.