Exemestane依西美坦是一种选择性不可逆的芳香化酶抑制剂（Aromatase抑制剂，IC₅₀=27 nM）。Exemestane对人胎盘芳香化酶的Ki值为26 nM。

参考文献

[1] Miki Y, et al. Effects of aromatase inhibitors on human osteoblast and osteoblast-like cells: a possible androgenic bone protective effects induced by exemestane. Bone. 2007 Apr;40(4):876-87.

[2] Goss PE, et al. Effects of the steroidal aromatase inhibitor exemestane and the nonsteroidal aromatase inhibitor letrozole on bone and lipid metabolism in ovariectomized rats. Clin Cancer Res. 2004 Sep 1;10(17):5717-23.

-25~-15℃保存，有效期3年。避光干燥保存，避免反复冻融。