Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass . GDF8 is held in a latent state through interactions with its N-terminal prodomain.

高活性、高纯度、低内毒素、高批间一致性

ELISA Data 1:Immobilized Human/Mouse/Rat GDF-8, No Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human Activin RIIA, hFc Tag with the EC50 of 0.13 μg/ml determined by ELISA .

ELISA Data 2: Immobilized Human GDF-8, No Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 6.9 ng/ml determined by ELISA.

SPR Data 1: Human Activin RIIA, hFc Tag captured on CM5 Chip via Protein A can bind Human/Mouse/Rat GDF-8, No Tag with an affinity constant of 0.13 nM as determined in SPR assay .

SPR Data 2:Biotinylated Activin RIIB, His Tag captured on CM5 Chip via Streptavidin can bind Human/Mouse/Rat GDF-8, No Tag with an affinity constant of 0.24 nM as determined in SPR assay .

Cell Based Assay: Determined by its ability to inhibit the proliferation of MPC-11 cells. The expected ED50 for this effect is <30 ng/ml .

-25~-15℃保存，收到货之日起，有效期1年。复溶后， -85~-65℃保存，3个月有效期。避免反复冻融。