GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;ICC-1/100-1/200

Western blot analysis of Phospho-GSK3 (Tyr279/Tyr216) in 293 lysates using Phospho-GSK3 alpha/beta (Tyr279/Tyr216) antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Phospho-GSK3 (Tyr279/Tyr216) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Immunofluorescence analysis of Phospho-GSK3 (Tyr279/Tyr216) in Hela cells using GSK3a/b(Phospho-Tyr279/216) antibody(red).

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.