High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

推荐稀释比 FC:1/50-1/100

Flow Cytometry analysis of PBMC stained with CCR4 antibody(Red).Blue line histogram represents nonspecific negative control

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.