Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200

Immunofluorescence analysis of CD45 (8C1) in Human livercancer tissue using CD45 (8C1) antibody(red),and DAPI (blue).

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.