The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues.

Western

Western blot analysis of PTP1B (Phospho-Ser378) in Hela, A549, HL-60, U2OS lysates using Phospho-PTP1B (Ser378) antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human tonsil using PTP1B (Phospho-Ser378) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.