DMH-1 (DMH1)是一种有效的BMP受体选择性抑制剂,作用于人BMP I型受体ALK2,IC50为107.9 nM,能抑制BMP信号。BMP信号是调控胚胎发育的重要途径。此外,DMH-1对纯化的ALK5、AMPK、VEGFR-2和PDGFR没有明显抑制效果。
参考文献
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冰袋运输。粉末直接保存于-25~-15℃,有效期3年。建议干燥避光保存,避免反复冻融。