Ochromycinone (STA-21, STA21, (Rac)-STA-21)，又称抑胃酶氨酰-21，是STAT3的选择性抑制剂，具有抗炎、抗癌和抗菌活性。Ochromycinone通过抑制STAT3的DNA结合活性和二聚化来抑制STAT3活性。

参考文献

1.Song H, et al. A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells. Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4700-5.

2.Chen CJ, et al. Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells. BMC Cancer. 2007 Jun 28;7:111.

3.Park JS, et al. STA-21, a promising STAT-3 inhibitor that reciprocally regulates Th17 and Treg cells, inhibits osteoclastogenesis in mice and humans and alleviates autoimmune inflammation in an experimental model of rheumatoid arthritis. Arthritis Rheumatol. 2014, 66(4), 918-929.

冰袋运输。粉末直接保存于-20℃，有效期2年。建议分装后-20℃避光保存，避免反复冻融。