Baricitinib phosphate (LY3009104 phosphate,INCB028050 phosphate),又称巴瑞克替尼磷酸盐,是一种选择性、ATP竞争性、可口服的JAK1/2抑制剂,IC50值为5.9 nM和5.7 nM,对JAK3和Tyk2抑制活性较低,对c-Met和Chk2没有抑制作用。Baricitinib常用于治疗成人中中度至重度的活动性类风湿关节炎。
参考文献
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冰袋运输。粉末直接保存于-20℃,有效期2年。建议分装后-20℃避光保存,避免反复冻融。