CIL56(CA-3) 铁死亡诱导剂/YAP1/Tead转录活性抑制剂|CAS 300802-28-2（53548ES）

CIL56 (CIL-56, CA3, CA-3)是一种有效的选择性ferroptosis诱导剂，通过增加铁依赖性ROS诱导铁死亡。CIL56还能抑制YAP1/Tead转录活性，对YAP1高表达食管腺癌表现出抗癌活性。此外，CIL56可以通过脂质合成限速酶ACC1触发细胞死亡。

参考文献

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3.Song S, et al. A Novel YAP1 Inhibitor Targets CSC-Enriched Radiation-Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma. Mol Cancer Ther. 2018 Feb;17(2):443-454.

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