NU7026 (LY293646)是一种高效的DNA-PK/PI3K抑制剂，其IC₅₀值分别为0.23 μM/13 μM，对ATM和ATR无抑制活性。NU7026可加强G2/M周期阻滞和凋亡。

参考文献

[1] Veuger, S.J., et al. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly (ADP-ribose) polymerase-1. Cancer Res, 2003. 63(18): p. 6008-15.

[2] Nutley, B.P., et al. Preclinical pharmacokinetics and metabolism of a novel prototype DNA-PK inhibitor NU7026. Br J Cancer, 2005. 93(9): p. 1011-8.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。