Y-33075 (Y33075, Y-39983, Y39983) dihydrochloride是Y-33075盐酸盐形式，是从Y-27632衍生出来的一种有效ROCK抑制剂，IC₅₀值3.6 nM。相对于Y-27632，Y-33075对PKC和CaMKII抑制效果更好。

参考文献

[1].Hideki Tokushige, et al. Effects of Topical Administration of Y-39983, a Selective Rho-Associated Protein Kinase Inhibitor, on Ocular Tissues in Rabbits and Monkeys. Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3216-22.

[2].Tokushige H, et al. Effects of Y-39983, a selective Rho-associated protein kinase inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats. Curr Eye Res. 2011 Oct;36(10):964-70.

[3].Watabe H, et al. Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries. Jpn J Ophthalmol. 2011 Jul;55(4):411-417.

冰袋运输。粉末直接保存于-25~-15℃，有效期2年。建议干燥避光保存，避免反复冻融。