TUNEL细胞凋亡检测试剂盒(YSFluor 488) TUNEL Apoptosis Detection Kit（40307ES）

[ 1 ]Jmjd4 Facilitates Pkm2 Degradation in Cardiomyocytes and Is Protective Against Dilated Cardiomyopathy

[ 2 ]A Novel “Inside-Out” Intraocular Nanomedicine Delivery Mode for Nanomaterials’ Biological Effect Enhanced Choroidal Neovascularization Occlusion and Microenvironment Regulation

[ 3 ]Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer

[ 4 ]H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis

[ 5 ]Cholecystokinin coordinates gonadotropin-dependent and independent pathways to orchestrate zebrafish gonadal development

[ 6 ]Extracellular traps from activated vascular smooth muscle cells drive the progression of atherosclerosis

[ 7 ]Bifunctional Cx43 Mimic Peptide Grafted Hyaluronic Acid Hydrogels Inhibited Tumor Recurrence and Stimulated Wound Healing for Postsurgical Tumor Treatment

[ 8 ]Neutrophil Irgm1 Ameliorates Sepsis-Induced Myocardial Dysfunction by promoting Alox15 degradation

[ 9 ]CL-316243 facilitates stable atherosclerotic plaque phenotypes in association with suppression of perivascular adipose tissue ferroptosis via upregulating C/EBPβ

[ 10 ]RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging

[ 11 ]High-Performance Self-Cascade Pyrite Nanozymes for Apoptosis–Ferroptosis Synergistic Tumor Therapy

[ 12 ]The SUN1-SPDYA interaction plays an essential role in meiosis prophase I

[ 13 ]Structural repurposing of SGLT2 inhibitor empagliflozin for strengthening anti-heart failure activity with lower glycosuria

[ 14 ]Delivery of pOXR1 through an injectable liposomal nanoparticle enhances spinal cord injury regeneration by alleviating oxidative stress

[ 15 ]Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy

[ 16 ]HSP90AB1-Mediated Ubiquitin-Proteasome Degradation of ITGBL1 Promotes Osteosarcoma Progression by Inhibiting Endoplasmic Reticulum Stress-Induced Autophagy

[ 17 ]Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis

[ 18 ]NSD2 Coordinates the Neurogenic-to-Gliogenic Transition via H3K36me2-Dependent Activation of the EGFR-ERK Pathway

[ 19 ]Mesenchymal stem cells receive adaptive islet–derived miR-151–containing sEVs to promote β cell compensation in obesity

[ 20 ]Copper Silicate Hollow Microspheres-Incorporated Scaffolds for Chemo-Photothermal Therapy of Melanoma and Tissue Healing

[ 21 ]FAAH initiates a positive feedback loop to promote lung adenocarcinoma progression through inhibition of ferroptosis

[ 22 ]Postnatal exposure to low-dose tetrabromobisphenol A increases the susceptibility of mammal testes to chemical-induced spermatogenic stress in adulthood

[ 23 ]Calcium silicate-human serum albumin composite hydrogel decreases random pattern skin flap necrosis by attenuating vascular endothelial cell apoptosis and inflammation

[ 24 ]40 Hz transcranial ultrasound stimulation improves cognition and neuroinflammation in female Alzheimer's disease mice

[ 25 ]NLRP3/Caspase-1 Regulate Macrophage Efferocytosis by Modulating ADAM17-Mediated MerTK Cleavage in Liver Ischemia–Reperfusion Injury

[ 26 ]HSP101-encoding NEO-TETRAPLOID RICE FERTILITY GENE 1 regulates tapetum development through interaction with SAPK2 in polyploid rice

[ 27 ]ABRO1 arrests cardiomyocyte proliferation and myocardial repair by suppressing PSPH

[ 28 ]FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis

[ 29 ]NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux

[ 30 ]The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope

[ 31 ]Histamine H2 receptor negatively regulates oligodendrocyte differentiation in neonatal hypoxic-ischemic white matter injury

[ 32 ]Targeting glutamine utilization to block metabolic adaptation of tumor cells under the stress of carboxyamidotriazole-induced nutrients unavailability

[ 33 ]SGK1 inhibition supports neuroprotection in spinal cord injury by suppressing oxidative stress and AIM2 activation via FoxO1 mediated mitophagy

[ 34 ]Complement C5a/C5aR1 pathway facilitates glioblastoma progression via fostering glioma stem cell-macrophage symbiosis

[ 35 ]Selenium sulfide disrupts the PLAGL2/C-MET/STAT3-induced resistance against mitochondrial apoptosis in hepatocellular carcinoma

[ 36 ]Modified CFBP-bFGF targeting to ischemic brain promoted the functional recovery of cerebral ischemia

[ 37 ]TRIM21 deficiency protects against atrial inflammation and remodeling post myocardial infarction by attenuating oxidative stress

[ 38 ]Promoting Tumor Accumulation of Anticancer Drugs by Hierarchical Carrying of Exogenous and Endogenous Vehicles

[ 39 ]Carbonized Typhae Pollen coordinates VEGF-dependent hemostatic and vascular protective pathways in blood stasis syndrome

[ 40 ]Inhibition of retinoic acid receptor α phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3

[ 41 ]Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis

[ 42 ]Miltefosine exhibits fungicidal activity through oxidative stress generation and Aif1 activation in Candida albicans

[ 43 ]Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response

[ 44 ]Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction

[ 45 ]Mechanisms of D‑tetramethrin‑induced neurotoxicity and locomotor abnormalities in zebrafish embryos revealed by transcriptomic analysis

[ 46 ]An atherosclerotic plaque-targeted single-chain antibody for MR/NIR-II imaging of atherosclerosis and anti-atherosclerosis therapy

[ 47 ]Gasdermin D mediates doxorubicin-induced cardiomyocyte pyroptosis and cardiotoxicity via directly binding to doxorubicin and changes in mitochondrial damage

[ 48 ]CaCO3-Encapuslated Microspheres for Enhanced Transhepatic Arterial Embolization Treatment of Hepatocellular Carcinoma

[ 49 ]Biomimetic PLGA-based nanocomplexes for improved tumor penetration to enhance chemo-photodynamic therapy against metastasis of TNBC

[ 50 ]Juxtamembrane 2 mimic peptide competitively inhibits mitochondrial trafficking and activates ROS-mediated apoptosis pathway to exert anti-tumor effects

[ 51 ]Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice

[ 52 ]Bio-nanocomplexes with autonomous O2 generation efficiently inhibit triple negative breast cancer through enhanced chemo-PDT

[ 53 ]Inhibition of Dot1L Alleviates Fulminant Hepatitis Through Myeloid-Derived Suppressor Cells

[ 54 ]Mechanism of mitochondrial biogenesis regulated by PGC-1α/NR1D1 to increase the vulnerability of myocardial ischemia/reperfusion injury in diabetes

[ 55 ]Bisphenol A and Bisphenol S Disrupt Placental Epithelial - Mesenchymal Transition and Angiogenesis via Activating Endoplasmic Reticulum Stress

[ 56 ]A Peptide from Budding Yeast GAPDH Serves as a Promising Antifungal against Cryptococcus neoformans

[ 57 ]Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer

[ 58 ]ROS-Activatable siRNA-Engineered Polyplex for NIR-Triggered Synergistic Cancer Treatment

[ 59 ]Cytidine/Uridine monophosphate kinase 2 promotes aflatoxin B1-induced hepatic pyroptosis and inflammation

[ 60 ]TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress

[ 61 ]Fructose-coated Angstrom silver inhibits osteosarcoma growth and metastasis via promoting ROS-dependent apoptosis through the alteration of glucose metabolism by inhibiting PDK

[ 62 ]Macrophage-derived extracellular vesicles regulate follicular activation and improve ovarian function in old mice by modulating local environment

[ 63 ]Combined Cyclin-Dependent Kinase Inhibition Overcomes MAPK/Extracellular Signal–Regulated Kinase Kinase Inhibitor Resistance in Plexiform Neurofibroma of Neurofibromatosis Type I

[ 64 ]GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure

[ 65 ]Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response

[ 66 ]The flavonoid GL-V9 induces oxidative stress mediated apoptosis in small cell lung cancer by promoting STEAP3 degradation

[ 67 ]Biomimetic Self-Assembled Chlorin e6/Capsaicin nanoparticles for Hypoxia-Alleviated photodynamic therapy of Triple-Negative breast cancer

[ 68 ]CDK5RAP3, a key defender of udder, modulates NLRP3 inflammasome activation by regulating autophagolysosome degradation in S. agalactiae-infected mastitis

[ 69 ]Celastrol Targets Hsc70-Bim Interaction as a Novel Senolytic to Extend Lifespan and Mitigate Organ Fibrosis

[ 70 ]Sodium molybdate inhibits the growth of ovarian cancer cells via inducing both ferroptosis and apoptosis

[ 71 ]The RNA-binding protein CSTF2 regulates BAD to inhibit apoptosis in glioblastoma

[ 72 ]Porous Se@SiO2 nanocomposite promotes migration and osteogenic differentiation of rat bone marrow mesenchymal stem cell to accelerate bone fracture healing in a rat model

[ 73 ]Natural pollen extract for photothermal therapy

[ 74 ]Hematopoietic stem cell and immunotoxicity in zebrafish embryos induced by exposure to Metalaxyl-M

[ 75 ]Microfluidic fabrication of inhalable large porous microspheres loaded with H2S-releasing aspirin derivative for pulmonary arterial hypertension therapy

[ 76 ]Prenatal glucocorticoids exposure disrupts maturation of a cluster of microglia, causing poor social memory and more repetitive behaviors

[ 77 ]eIF4E2 deficiency translationally unleashes WRN to sustain DNA repair-mediated chemoresistance

[ 78 ]Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma

[ 79 ]Potential effects of bexarotene on neural development and function in zebrafish embryos

[ 80 ]TNF-α/IL-1β-licensed hADSCs alleviate cholestatic liver injury and fibrosis in mice via COX-2/PGE2 pathway

[ 81 ]Yixinshu attenuates myocardial infarction via SHP1/JAK2/STAT3-mediated regulation of mitochondrial function and apoptosis

[ 82 ]Pretreatment with Panaxatriol Saponin Attenuates Mitochondrial Apoptosis and Oxidative Stress to Facilitate Treatment of Myocardial Ischemia-Reperfusion Injury via the Regulation of Keap1/Nrf2 Activity

[ 83 ]CORM-3 Attenuates Oxidative Stress-Induced Bone Loss via the Nrf2/HO-1 Pathway

[ 84 ]Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury

[ 85 ]Extracellular vesicles from human urine-derived stem cells inhibit glucocorticoid-induced osteonecrosis of the femoral head by transporting and releasing pro-angiogenic DMBT1 and anti-apoptotic TIMP1

[ 86 ]Procymidone induces muscle atrophy and impaired myocyte fusion via the TNF-α/NF-κB/ROS pathway in developing zebrafish embryos

[ 87 ]Extraction, purification, and determination of the gastroprotective activity of glucomannan from Bletilla striata

[ 88 ]TBK1-medicated DRP1 phosphorylation orchestrates mitochondrial dynamics and autophagy activation in osteoarthritis

[ 89 ]Myostatin knockout induces apoptosis in human cervical cancer cells via elevated reactive oxygen species generation

[ 90 ]ARC regulates programmed necrosis and myocardial ischemia/reperfusion injury through the inhibition of mPTP opening

[ 91 ]Long noncoding RNA NONMMUT015745 inhibits doxorubicin-mediated cardiomyocyte apoptosis by regulating Rab2A-p53 axis

[ 92 ]Hsa-miR-1908-3p Mediates the Self-Renewal and Apoptosis of Human Spermatogonial Stem Cells via Targeting KLF2

[ 93 ]Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy

[ 94 ]Matrine protects colon mucosal epithelial cells against inflammation and apoptosis via the Janus kinase 2 /signal transducer and activator of transcription 3 pathway

[ 95 ]MiRNA-99a alleviates inflammation and oxidative stress in lipopolysaccharide-stimulated PC-12 cells and rats post spinal cord injury

[ 96 ]Galangin alleviates rheumatoid arthritis in rats by downregulating the phosphatidylinositol 3-kinase/protein kinase B signaling pathway

[ 97 ]CircCAMSAP1 promotes non-small cell lung cancer proliferation and inhibits cell apoptosis by sponging miR-1182 and regulating BIRC5

[ 98 ]Shengxian Decoction mitigate bleomycin-induced pulmonary fibrosis in mice via MerTK mediated macrophage efferocytosis

[ 99 ]Albendazole exerts an anti-hepatocellular carcinoma effect through a WWOX-dependent pathway

[ 100 ]Hsa-miR-100-3p Controls the Proliferation, DNA Synthesis, and Apoptosis of Human Sertoli Cells by Binding to SGK3