Costunolide，又称木香烃内酯，是天然的倍半萜内酯，具有多种生物活性。Costunolide通过阻断血管生长因子信号来抑制血管生成，对平滑肌有解痉作用，也具有抗炎、抗氧化作用。

参考文献

[1] Choi SH, Im E, Kang HK, et al. Inhibitory effects of costunolide on the telomerase activity in human breast carcinoma cells. Cancer Lett. 2005 Sep 28;227(2):153-62. doi: 10.1016/j.canlet.2005.01.011(IF:6.508).

[2] Kim DY, Kim DY. Costunolide-A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential. Int J Mol Sci. 2019 Jun 14;20(12):2926. doi: 10.3390/ijms20122926(IF:4.183).

[3] Peng Z, Wang Y, Fan J, et al. Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway. Sci Rep. 2017 Jan 24;7:41254. doi: 10.1038/srep41254(IF:4.01).

[4] Jeong SJ, Itokawa T, Shibuya M, et al. Costunolide, a sesquiterpene lactone from Saussurea lappa, inhibits the VEGFR KDR/Flk-1 signaling pathway. Cancer Lett. 2002 Dec 10;187(1-2):129-33. doi: 10.1016/s0304-3835(02)00361-0(IF:6.508).

-25~-15℃保存，有效期3年。