翌圣生物提供高品质DSS（60316ES）：高纯度（98%），硫含量17-19%，游离硫＜0.2%，有大量文献数据支持，助力结肠炎模型构建。

产品官网链接

DSS结肠炎建模用葡聚糖硫酸钠盐 Mw 36000~50000 Dextran Sulfate Sodium Salt

相关专题链接

1.Dextran Sulfate Sodium Salt（DSS）结肠炎造模解决方案

2.干货分享 | DSS诱导建立慢性和急性动物结肠炎模型的解决方案

3.如何评价DSS诱导结肠炎模型是否成功

4.动物实验系列产品-选购指南

翌圣DSS客户数据展示（列举）

客户1 ：

客户来源：浙江大学

小鼠类型：6周龄雄性C57BL/6小鼠

造模方法：3个周期，每个周期包括1周2% DSS，2周饮用水。

图1.Yeasen DSS（Cat#60316ES）小鼠造模实验结果（Zhong D, Jin K, Wang R,et al. Microalgae-Based Hydrogel for Inflammatory Bowel Disease and Its Associated Anxiety and Depression. Advanced Materials. 2024. IF=29.4）

客户2：

客户来源：上海交通大学医学院瑞金医院

小鼠类型：9周龄雌性C57BL/6J小鼠

造模方法：4% (w/v) DSS自由饮用10天。

图2 .Yeasen DSS（Cat#60316ES）小鼠造模实验结果（Li Zhao, et al. Chemical Engineering Journal. 2021.130464. IF=13.27）

客户3：

客户来源：中国医学科学院北京协和医学院放射医学研究所(天津)

小鼠类型：6~8周雄性C57BL/6J小鼠

造模方法：1.5% (w/v) DSS自由饮用15天。

图3.Yeasen DSS（Cat#60316ES）小鼠造模实验结果（Yuan Li, et al. Gut Microbes.2019.789-806. IF=10.245）

客户发表文献（不完全统计） 

[1] Zhong D, Jin K, Wang R, Chen B, Zhang J, Ren C, Chen X, Lu J, Zhou M. Microalgae-Based Hydrogel for Inflammatory Bowel Disease and Its Associated Anxiety and Depression. Adv Mater. 2024 Jan 26: e2312275. doi: 10.1002/adma.202312275. Epub ahead of print. PMID: 38277492.IF: 29.4

[2] Zhang Y, Tu S, Ji X, Wu J, Meng J, Gao J, Shao X, Shi S, Wang G, Qiu J, Zhang Z, Hua C, Zhang Z, Chen S, Zhang L, Zhu SJ. Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway. Nat Commun. 2024 Feb 13;15(1):1333. doi: 10.1038/s41467-024-45636-x.IF: 16.6

[3] Li Zhao, Fei Wang,Zhengwei Cai,et al.Improving drug utilization platform with injectable mucoadhesive hydrogel for treating ulcerative colitis[J].chemical engineering journal.424(2021)130464.IF=16.744

[4] Lingjun Tong, Haining Hao, Zhe Zhang,et al.Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota[J].Theranostics.2021; 11(17): 8570-8586. IF=11.556

[5] Li, Y., Dong, J., Xiao, H., Zhang, S., Wang, B., Cui, M., & Fan, S. Gut commensal derived-valeric acid protects against radiation injuries. Gut Microbes,.2020 .1–18.IF=10.245

[6] Jingjing Gan, Yuxiao Liu, Lingyu Sun,et al.Orally administrated nucleotide-delivery particles from microfluidics for inflammatory bowel disease treatment[J].Applied Materials Today.2021 Dec;25:101231. IF=10.041

[7] JialiDong,YuanLi,HuiwenXiao,et al.Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models[J].Cell reports.2021, 109886.IF=9.423

[8] Hao H,  Zhang X,  Tong L,  Liu Q,et al.Lactobacillus plantarumEffect of Extracellular Vesicles Derived From  Q7 on Gut Microbiota and Ulcerative Colitis in Mice[J].Frontiers in Immunology.2021.777147.IF=7.561

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