CD40 is a transmembrane protein widely expressed in antigen-presenting cells, B cells, and other immune cells. It plays a vital role in regulating immune response by providing signals for activation, proliferation, and differentiation of lymphocytes. Furthermore, CD40 is a crucial target for cancer immunotherapy due to its involvement in promoting tumor immunity.
性能参数
Synonyms |
CD40;Bp50;CDW40;MGC9013;TNFRSF5;p50 |
Uniprot No. |
P25942 |
Source |
Recombinant Human CD40 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Glu21-Arg193. |
Molecular Weight |
The protein has a predicted MW of 21.1 kDa. And it migrates as 33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Purity |
> 95% as determined by SDS-PAGE. |
Endotoxin |
<1 EU per 1μg of the protein by the LAL method. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
Reconstitution |
Centrifuge tubes before opening. Dissolve lyophilized protein with sterile PBS to ensure the concentration is greater than 100 ug/mL. |
储存条件
The product should be stored at -25~-15℃ for 1 year from date of receipt.
2-7 days, 2 ~8 °C under sterile conditions after reconstitution.
3 months, -25~-15℃ under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
注意事项
1.Please operate with lab coats and disposable gloves,for your safety.
2.This product is for research use only.
产品数据
Ver. CN20230531