Cap AU is a cap analogue with the structure of m7G(5')ppp(5')(2'OMeA)pU, the molecular formula of it is C₃₁H₄₂N₁₂O₂₅P₄ and the molecular weight is 1106.6. The product is specifically designed for self-replicating RNAs based on the genomes of positive sense strand RNA viruses such as Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN).

The (+) strand genomes of these viruses start with a 5’-AU… Cap 1 mRNAs have superior in vivo activity compared to Cap 0 mRNA produced by legacy co-transcriptional capping methods anti-reverse cap analog (ARCA).

This product is produced in accordance with GMP process requirements and provided in liquid form.

 

Product Nature

Molecular Formula	C31H42N12O25P4 (free acid)
Molecular weight	1106.6 (free acid)
Concentration	100 ± 3mM
Purity	≥ 98%
Structure

 

Shipping and Storage

This product is shipped with dry ice and can be stored at -25℃ ~ -15℃ for two years.

 

Notes

1. For your safety and health, please wear personal protective equipment (PPE), such as laboratory coats and disposable gloves, when operating with this product.

 

HB230226