Axl, is a widely expressed glycoprotein in the TAM receptor tyrosine kinase family. TAM family receptors (Dtk/Tyro3, Axl, and Mer) are involved in regulation of the inflammatory response, cell survival and migration, and tumorigenesis. Axl is highly expressed in solid cancers and promotes in vivo tumorigenesis and tumor cell invasiveness. It contributes to vascular remodeling and inflammatory cell infiltration in response to hypertension and restricted blood flow.
产品性质
别名 |
Axl; UFO; AXL oncogene; AXL; ARK; JTK11; Tyro7; AI323647; EC 2.7.10; EC 2.7.10.1 |
Uniprot No. |
P30530.1 |
表达区间及表达系统 |
Biotinylated Recombinant Human Axl Protein is expressed from HEK293 Cells with His-Avi tag at the C-terminal. It contains Ala26-Pro449. |
分子量 |
The protein has a predicted MW of 48.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
纯度 |
> 95% as determined by SDS-PAGE and HPLC. |
内毒素 |
< 1.0 EU per 1μg of the protein by the LAL method. |
制剂 |
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization. |
复溶 |
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water. |
运输与保存方法
冰袋运输。-20℃保存,一年有效期。
复溶后,-20 至 -80°C,在未开封状态下保存 3-6 个月。复溶后,2-8°C 保存 2-7 天。
建议第一次使用时分装冻存,避免反复冻融。
注意事项
1.为了您的安全和健康,请穿实验服并戴一次性手套操作。
2.本产品仅作科研用途!
产品数据
HB230203