RIPA裂解液(中)|RIPA Lysis Buffer(Medium) 裂解缓冲液（20115ES）

[ 1 ]Exacerbation of allergic rhinitis by the commensal bacterium Streptococcus salivarius

[ 2 ]Cancer cell-derived exosomal circUSP7 induces CD8+ T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC

[ 3 ]FBXO6 regulates the antiviral immune responses via mediating alveolar macrophages survival

[ 4 ]FOXI3 establishes the ectodermal niche in pharyngeal arches for cranial neural crest cells and their lineages

[ 5 ]Molecular basis of host ATP level modulation by actin-dependent secreted bacterial ATPase and its metaeffector

[ 6 ]Vision rescue via unconstrained in vivo prime editing in degenerating neural retinas

[ 7 ]Cholesterol-depleted macrophage membrane-coated nano-rapamycin for targeted atherosclerosis therapy

[ 8 ]LACC1 attenuates LPS-induced acute lung injury by inhibiting inflammatory response in alveolar macrophage through LPAR3/PI3K/AKT/mTOR signaling pathway

[ 9 ]Molecular architecture responsible for specific inhibition of oncogenic PI3Kα mutants by RLY-2608 and STX-478

[ 10 ]Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2-arm mRNA Platform

[ 11 ]SHANK3 mutations disrupt olfactory valence coding across species, with cortical amygdala mechanisms identified in mice

[ 12 ]A short period of early life oxytocin treatment rescues social behavior dysfunction via suppression of hippocampal hyperactivity in male mice

[ 13 ]Tumor progress intercept by intervening in Caveolin-1 related intercellular communication via ROS-sensitive c-Myc targeting therapy

[ 14 ]Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling

[ 15 ]TRIM28-mediated SUMOylation of SREBF1 drives PD‑L1 N‑glycosylation and immune evasion in bladder cancer

[ 16 ]Myosin VI drives breast cancer progression via SP1/CA9-mediated acidic tumor microenvironment remodeling and subsequent M2 macrophage polarization

[ 17 ]Glycogen synthase 1 promotes breast cancer progression by promoting IκBα ubiquitination and degradation independent of its canonical enzyme function

[ 18 ]Afzelin resists UVA damage through autophagy and synergizes with ganoderic acid A to skin photoaging

[ 19 ]A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer

[ 20 ]CRYL1 inhibits tumorigenesis and metastasis in clear cell renal cell carcinoma through upregulation of CASR

[ 21 ]Original research: ANKRD22 is a potential novel target for reversing the immunosuppressive effects of PMN-MDSCs in ovarian cancer

[ 22 ]Arsenic retention in erythrocytes and excessive erythrophagocytosis is related to low selenium status by impaired redox homeostasis

[ 23 ]Soft substrates promote direct chemical reprogramming of fibroblasts into neurons

[ 24 ]Freeze-casting osteochondral scaffolds: The presence of a nutrient-permeable film between the bone and cartilage defect reduces cartilage regeneration

[ 25 ]Aquaporin 11 alleviates retinal Müller intracellular edema through water efflux in diabetic retinopathy

[ 26 ]DCBLD1 Promotes Lung Tumorigenesis by Inhibiting PTP1B Dephosphorylation of EGFR

[ 27 ]Therapeutic inhibition of PPARα-HIF1α-PGK1 signaling targets leukemia stem and progenitor cells in acute myeloid leukemia

[ 28 ]Juxtamembrane 2 mimic peptide competitively inhibits mitochondrial trafficking and activates ROS-mediated apoptosis pathway to exert anti-tumor effects

[ 29 ]The structural basis for glycerol permeation by human AQP7

[ 30 ]USP39 stabilizes β-catenin by deubiquitination and suppressing E3 ligase TRIM26 pre-mRNA maturation to promote HCC progression

[ 31 ]MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor

[ 32 ]Protective effect of resveratrol against colistin-induced nephrotoxicity through regulating Nrf2 pathway and inhibiting ferroptosis

[ 33 ]Retrograde regulation of mitochondrial fission and epithelial to mesenchymal transition in hepatocellular carcinoma by GCN5L1

[ 34 ]Increased yolk lipid mobilization promotes zebrafish post-segmentation growth via an Hnf4-lipoprotein axis

[ 35 ]ROS-scavenging glyco-nanoplatform for synergistic antibacterial and wound-healing therapy of bacterial keratitis

[ 36 ]PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during fasting by modulating protein stability of PPARα

[ 37 ]Efficient iron utilization compensates for loss of extracellular matrix of ovarian cancer spheroids

[ 38 ]Decreased expression of IDH1 by chronic unpredictable stress suppresses proliferation and accelerates senescence of granulosa cells through ROS activated MAPK signaling pathways

[ 39 ]Never-in-Mitosis A-Related Kinase 8 (NEK8) Regulates Adipogenesis, Glucose Homeostasis, and Obesity

[ 40 ]Spermidine induces cytoprotective autophagy of female germline stem cells in vitro and ameliorates aging caused by oxidative stress through upregulated sequestosome-1/p62 expression

[ 41 ]Comparison of RNA m6A and DNA methylation profiles between mouse female germline stem cells and STO cells

[ 42 ]circPVT1 regulates EMT and induces macrophage polarization to promotes the progression of renal cell carcinoma

[ 43 ]Hsa_circ_0039569 facilitates the progression of endometrial carcinoma by targeting the miR-197/high mobility group protein A1 axis

[ 44 ]MiRNA-99a alleviates inflammation and oxidative stress in lipopolysaccharide-stimulated PC-12 cells and rats post spinal cord injury

[ 45 ]Circular RNA hsa_circ_0001658 regulates apoptosis and autophagy in gastric cancer through microRNA-182/Ras-related protein Rab-10 signaling axis

[ 46 ]C-X-C motif chemokine ligand 12 (CXCL12)/C-X-C motif chemokine receptor 7(CXCR7) regulates epithelial-mesenchymal transition process and promotes the metastasis of esophageal cancer by activating signal transducer and activator of transcription 3 (STAT3) pathway

[ 47 ]Noncoding-RNA mediated high expression of zinc finger protein 268 suppresses clear cell renal cell carcinoma progression by promoting apoptosis and regulating immune cell infiltration

[ 48 ]Integrated bioinformatics and machine learning approaches reveal that Venenum bufonis acts against acute pharyngitis by inhibiting the p38 MAPK/ERK-MKNK1-eIF4E signaling pathway

[ 49 ]Design and syntheses of a bimolecular STING agonist based on the covalent STING antagonist

[ 50 ]Daidzein Activates Akt Pathway to Promote the Proliferation of Female Germline Stem Cells through Upregulating Clec11a

[ 51 ]BMSC-Derived Small Extracellular Vesicles Induce Cartilage Reconstruction of Temporomandibular Joint Osteoarthritis via Autotaxin–YAP Signaling Axis

[ 52 ]FOXO4 Inhibits the Migration and Metastasis of Colorectal Cancer by Regulating the APC2/β-Catenin Axis

[ 53 ]SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway

[ 54 ]Sphingomyelin-Sequestered Cholesterol Domain Recruits Formin-Binding Protein 17 for Constricting Clathrin-Coated Pits in Influenza Virus Entry

[ 55 ]Antiaging Effects of Vicatia thibetica de Boiss Root Extract on Caenorhabditis elegans and Doxorubicin-Induced Premature Aging in Adult Mice

[ 56 ]GSK2879552 inhibits NLRP3 inflammasome-mediated pyroptosis and acute lung injury through NOX2-ROS signalling axis

[ 57 ]Solanum nigrum L.-derived nanovesicles as novel nanotherapeutics suppressing prostate cancer progression via senescence-based antitumor activity

[ 58 ]Pretreatment with chitosan oligosaccharides attenuate experimental severe acute pancreatitis via inhibiting oxidative stress and modulating intestinal homeostasis

[ 59 ]Cytotoxic Effect of a β1,4-Galactosyltransferase Inhibitor in Hepatic Carcinoma Cells

[ 60 ]Flaxseed Powder Attenuates Non-Alcoholic Steatohepatitis via Modulation of Gut Microbiota and Bile Acid Metabolism through Gut–Liver Axis

[ 61 ]GAS5/miR-21 Axis as a Potential Target to Rescue ZCL-082-Induced Autophagy of Female Germline Stem Cells In Vitro

[ 62 ]Antibiotics administration during weaning ameliorates intestinal mucosal inflammation in adult mice and their offspring

[ 63 ]Characterization and Heterologous Expression of UDP-Glucose 4-Epimerase From a Hericium erinaceus Mutant with High Polysaccharide Production

[ 64 ]Improvement of Non-Alcoholic Fatty Liver Disease in Mice by Intermittent Use of a Fasting-Mimicking Diet

[ 65 ]Inter-Fighting between Influenza A Virus NS1 and β-TrCP: A Novel Mechanism of Anti-Influenza Virus

[ 66 ]The Marine-Derived Cyclopentapeptide Turnagainolide B Suppresses Melanoma via Autophagic Flux Disruption and Inhibits Tumorigenesis In Vivo

[ 67 ]LncRNA OTUD6B-AS1 promotes paclitaxel resistance in triple negative breast cancer by regulation of miR-26a-5p/MTDH pathway-mediated autophagy and genomic instability

[ 68 ]C89 Induces Autophagy of Female Germline Stem Cells via Inhibition of the PI3K-Akt Pathway In Vitro

[ 69 ]Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7

[ 70 ]TIPE2 inhibits PDGF-BB-induced phenotype switching in airway smooth muscle cells through the PI3K/Akt signaling pathway

[ 71 ]Carboxylated Agarose (CA)-Silk Fibroin (SF) Dual Confluent Matrices Containing Oriented Hydroxyapatite (HA) Crystals: Biomimetic Organic/Inorganic Composites for Tibia Repair

[ 72 ]Vicatia thibetica de Boiss Crude Polysaccharide Delay the Aging of the Heart and Kidneys

[ 73 ]Buyang Huanwu Decoction Attenuates Infiltration of Natural Killer Cells and Protects Against Ischemic Brain Injury

[ 74 ]Polysaccharides from Ulva prolifera O.F. Müller inhibit cell proliferation via activating MAPK signaling in A549 and H1650 cells

[ 75 ]Transcriptomic analysis reveals that the anti-PCOS effects of Zishen Qingre Lishi Huayu recipe may involve pathways and genes related to autophagy, steroidogenesis, oxidative stress, and inflammation in granulosa cells

[ 76 ]Homeostatic Regulation of Astrocytes by Visual Experience in the Developing Primary Visual Cortex

[ 77 ]124I Radiolabeled Basiliximab for CD25-Targeted Immuno-PET Imaging of Activated T Cells

[ 78 ]Novel insights into antidepressant mechanism of Kai Xin San formula: Inhibiting NLRP3 inflammasome activation by promoting autophagy

[ 79 ]Busulfan Suppresses Autophagy in Mouse Spermatogonial Progenitor Cells via mTOR of AKT and p53 Signaling Pathways

[ 80 ]Ubiquitin-Specific-Processing Protease 7 Regulates Female Germline Stem Cell Self-Renewal Through DNA Methylation

[ 81 ]Salidroside ameliorates skin aging in male mice by promoting collagen regeneration via modulation of FOS and MMP9

[ 82 ]CaSR regulates SLC26A6 expression via the PKA-FOXO4 signaling axis to promote experimental calcium oxalate kidney stone formation in rats

[ 83 ]Enhancing fractalkine/CX3CR1 signalling pathway can reduce neuroinflammation by attenuating microglia activation in experimental diabetic retinopathy

[ 84 ]Identification of the Prognostic Value Among Suppressor Of Cytokine Signaling Family Members in Kidney Renal Clear Cell Carcinoma

[ 85 ]Long noncoding RNA LYPLAL1-AS1 regulates adipogenic differentiation of human mesenchymal stem cells by targeting desmoplakin and inhibiting the Wnt/β-catenin pathway

[ 86 ]Structurally diverse steroids from an endophyte of Aspergillus tennesseensis 1022LEF attenuates LPS-induced inflammatory response through the cholinergic anti-inflammatory pathway

[ 87 ]Apigenin suppresses tumor angiogenesis and growth via inhibiting HIF-1α expression in non-small cell lung carcinoma

[ 88 ]The transcribed ultraconserved element uc.51 promotes the proliferation and metastasis of breast cancer by stabilizing NONO

[ 89 ]Demethylenetetrahydroberberine alleviates nonalcoholic fatty liver disease by inhibiting the NLRP3 inflammasome and oxidative stress in mice

[ 90 ]CNDP2 drives renal tubular fibrosis in diabetic kidney disease via a sulfur-containing amino acids-mTOR signaling axis

[ 91 ]Co-delivery of PDL1-blocking scFv and chemotherapeutics using engineered exosomes for cancer therapy

[ 92 ]Chicken STING Mediates Activation of the IFN Gene Independently of the RIG-I Gene

[ 93 ]lnc-ALX1-2:10 is a novel regulator that enhances proliferation, migration and invasion in prostate cancer cells

[ 94 ]The Imbalance of Mitochondrial Fusion/Fission Drives High-Glucose-Induced Vascular Injury

[ 95 ]FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors

[ 96 ]The underlying mechanism of scorpion venom peptide BmK AS in reducing epilepsy seizures: mediated through dual modulation of Nav1.6 and the inflammasome pathway

[ 97 ]T-cell infiltration in the central nervous system and their association with brain calcification in Slc20a2-deficient mice

[ 98 ]Dexmedetomidine inhibits microglia activation, neuroinflammation, and glycolysis in postoperative cognitive dysfunction by promoting YTHDF2-mediated PKM2 mRNA degradation

[ 99 ]Synthesis and Biological Evaluation of Isomeric Artemisinin Trimers as Novel Antitumor Agents

[ 100 ]Autophagy negative-regulating Wnt signaling enhanced inflammatory osteoclastogenesis from Pre-OCs in vitro