SU5402 (SU-5402)是一种多靶点的VEGF、FGF和PDGF受体酪氨酸激酶抑制剂，SU5402抑制VEGFR2、FGFR1、PDGFRβ和EGFR依赖性细胞增殖，其IC50值分别为20 nM、30 nM、510 nM和 > 100 μM。在鼻咽上皮细胞中，SU5402减弱LMP1-介导的有氧糖酵解，细胞转化，细胞迁移和侵袭。

参考文献

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冰袋运输。粉末直接保存于-20℃，有效期2年。溶于DMSO。建议分装后-20℃避光保存，避免反复冻融。