[ 1 ]METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability

[ 2 ]Pentose phosphate pathway fuels cGAS-STING signalling to boost function of intratumoral conventional dendritic cells

[ 3 ]O-GlcNAcylation of AMFR stabilizes TSPAN4 to regulate migrasome formation for viral release

[ 4 ]Automated high-throughput genome editing platform with an AI learning in situ prediction model

[ 5 ]Molecular mechanism of agonism and inverse agonism in ghrelin receptor

[ 6 ]Insights into membrane association of the SMP domain of extended synaptotagmin

[ 7 ]Histone tyrosine sulfation by SULT1B1 regulates H4R3me2a and gene transcription

[ 8 ]Genetic Control of Tissue Remodeling by a Non-Coding SNP in ITGA8 Explains Carotenoid-Based Color Polymorphism in Marine Mollusks

[ 9 ]Neuroprotective response against the onset of ischemic stroke by upregulation of histone H3Y99 sulfation

[ 10 ]mTOR-NAA10-C7orf50 axis senses nutritional status to coordinate ribosome biogenesis and autophagy

[ 11 ]CLOCK-catalyzed histone H3K37 glutarylation suppresses H3K36 trimethylation pathways in glioblastoma

[ 12 ]Mechanism of sphingolipid homeostasis revealed by structural analysis of Arabidopsis SPT-ORM1 complex

[ 13 ]CRL4B complex-mediated H2AK119 monoubiquitination restrains Th1 and Th2 cell differentiation

[ 14 ]Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment

[ 15 ]Ethyl ferulate suppresses choroidal neovascularization by accelerating Keap1 degradation through the inhibition of PSMD14-mediated deubiquitination

[ 16 ]Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication.

[ 17 ]A rationally designed bispecific antibody targeting GPC3 and PD-L1 induces tumor-directed immune activation and cytotoxicity

[ 18 ]Design, Synthesis, and Bioevaluation of 2-Aminopteridin-7(8H)-one Derivatives as Novel Potent Adenosine A2A Receptor Antagonists for Cancer Immunotherapy

[ 19 ]Spy&IAC enables specific capture of SpyTagged proteins for rapid assembly of plug-and-display nanoparticle vaccines

[ 20 ]Bio-engineered nano-vesicles for IR820 delivery: a therapy platform for cancer by surgery and photothermal therapy

[ 21 ]SEPHS2 loss reprograms cancer metabolism from oxidative phosphorylation to gluconeogenesis via PCK1 stabilization

[ 22 ]UFMylation-dependent inhibition of AKT signaling by PHLDA3 in lung adenocarcinoma

[ 23 ]Discovery of 2H-Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer Immunotherapy

[ 24 ]Discovery of Pyridinone Derivatives as Potent, Selective, and Orally Bioavailable Adenosine A2A Receptor Antagonists for Cancer Immunotherapy

[ 25 ]METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism

[ 26 ]Glioma-intrinsic SLC1A3 hijacks the vascular niche to establish an immunosuppressive microenvironment

[ 27 ]Lithocholic acid inhibits gallbladder cancer proliferation through interfering glutaminase-mediated glutamine metabolism

[ 28 ]Integrating single-cell and bulk transcriptomes to reveal prognostic and immunological features of ecDNA-related genes in osteosarcoma

[ 29 ]Multi-omics evaluation of cell lines as models for metastatic prostate cancer

[ 30 ]Proteomic and Phosphoproteomic Analyses Reveal the Oncogenic Role of PTK7-NDRG1 Axis in Non-small-cell Lung Cancer Cell Resistance to AZD9291

[ 31 ]Polystyrene nanoplastics promote tumor lung metastasis by inducing sodium overload in macrophages in an NMDAR-dependent way

[ 32 ]KAT5/8-mediated GPX4 lactylation facilitates ferroptosis and inflammation in diabetic retinopathy

[ 33 ]Development of an automated chemiluminescence immunoassay for detection of IgA antibodies against porcine epidemic diarrhea virus spike

[ 34 ]Effects study of SCGB2A2 on cell proliferation and milk components biosynthesis in ovine mammary epithelial cells

[ 35 ]Silencing TAB182 inhibits cell EMT, migration and invasion by downregulating EGFR in A549 NSCLC cells