[ 1 ]Sensory neurons drive immune exclusion by stimulating a dense extracellular matrix in the breast cancer tumor microenvironment

[ 2 ]CRLF1 Secreted by Cardiac Fibroblasts Promotes Human Hypertrophic Cardiomyopathy

[ 3 ]Restoration of dystrophin expression in mice by suppressing a nonsense mutation through the incorporation of unnatural amino acids

[ 4 ]Wnt3a promotes in situ dentin formation through NKD1-MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells

[ 5 ]Neuroendocrine Regulation of Stress-Induced T Cell Dysfunction during Lung Cancer Immunosurveillance via the Kisspeptin/GPR54 Signaling Pathway

[ 6 ]DSCAML1+ extracellular vesicles revealed by single-vesicle proteomics as a novel biomarker and therapeutic target in myocardial infarction

[ 7 ]EGFR- and HER3-targeted bispecific antibody-drug conjugate demonstrates anti-tumor activity in metastatic castration-resistant prostate cancer

[ 8 ]MVP Inhibits Influenza A Virus-Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

[ 9 ]Chemically Engineered L. reuteri Delivering αPD-L1 and Gallium Ions via Metal-Phenolic Networks Potentiate Anti-Tumor Immunity and Ferroptosis

[ 10 ]In vivo membrane engineering traps Gd-based MRI contrast agents for detecting microhepatocellular carcinoma

[ 11 ]Transcription-coupled structural dynamics of topologically associating domains regulate replication origin efficiency

[ 12 ]BIND&MODIFY: a long-range method for single-molecule mapping of chromatin modifications in eukaryotes

[ 13 ]c-Myc/GRPEL1 maintains fatty acid synthesis via FASN to support PDAC cell proliferation

[ 14 ]Conserved role of Atx2 in JNK pathway activation

[ 15 ]FcγRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape

[ 16 ]Recapitulating influenza virus infection and facilitating antiviral and neuroprotective screening in tractable brain organoids

[ 17 ]Molecular Mechanisms of Shenhong Tongluo Formula Against Myocardial Ischemia-Reperfusion Injury: Insights from RNA Sequencing, Bioinformatics, Reverse Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations Combined with Experimental Studies

[ 18 ]Palbociclib-based high-throughput combination drug screening identifies synergistic therapeutic options in HPV-negative head and neck squamous cell carcinoma

[ 19 ]Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance

[ 20 ]MYC-driven U2SURP regulates alternative splicing of SAT1 to promote triple-negative breast cancer progression

[ 21 ]HIF-α activation by the prolyl hydroxylase inhibitor roxadustat suppresses chemoresistant glioblastoma growth by inducing ferroptosis

[ 22 ]Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization

[ 23 ]A RIPK3-PGE2 Circuit Mediates Myeloid-Derived Suppressor Cell–Potentiated Colorectal Carcinogenesis

[ 24 ]Blocking P2X7-Mediated Macrophage Polarization Overcomes Treatment Resistance in Lung Cancer

[ 25 ]RIPK3 Orchestrates Fatty Acid Metabolism in Tumor-Associated Macrophages and Hepatocarcinogenesis

[ 26 ]Non-canonical function of an Hif-1α splice variant contributes to the sustained flight of locusts

[ 27 ]circCYP24A1 promotes Docetaxel resistance in prostate Cancer by Upregulating ALDH1A3

[ 28 ]MiR-93-5p Loaded Lipid Nanoparticles Break the Dry Eye Vicious Cycle via Targeting MAP3K8

[ 29 ]AF9-KLF2 gene regulatory circuit links histone lactylation to metabolic reprogramming and breast cancer progression

[ 30 ]Functional assessment of missense variants of uncertain significance in the cancer susceptibility gene PALB2

[ 31 ]Alternative End-Joining Dependency Imposed by miR-21-5p Defines Radiation Resistance and a Targetable Vulnerability in Oral Squamous Cell Carcinoma

[ 32 ]Chronic restraint stress promotes the mobilization and recruitment of myeloid-derived suppressor cells through β-adrenergic-activated CXCL5-CXCR2-Erk signaling cascades

[ 33 ]CircRFWD3 promotes HNSCC metastasis by modulating miR-27a/b/PPARγ signaling

[ 34 ]Comprehensive analysis of mitochondrial unfolded protein response related genes for prognosis and therapeutic response in pancreatic cancer

[ 35 ]Hsp90 Inhibitor STA9090 Sensitizes Hepatocellular Carcinoma to Hyperthermia-Induced DNA Damage by Suppressing DNA-PKcs Protein Stability and mRNA Transcription

[ 36 ]TNKS inhibitors potentiate proliferative inhibition of BET inhibitors via reducing β-Catenin in colorectal cancer cells

[ 37 ]Bile acid restrained T cell activation explains cholestasis aggravated hepatitis B virus infection

[ 38 ]Massively recruited sTLR9+ neutrophils in rapidly formed nodules at the site of tumor cell inoculation and their contribution to a pro-tumor microenvironment

[ 39 ]Nuclear receptor coactivator 6 promotes HTR-8/SVneo cell invasion and migration by activating NF-κB-mediated MMP9 transcription

[ 40 ]Chemotherapeutic Risk lncRNA-PVT1 SNP Sensitizes Metastatic Colorectal Cancer to FOLFOX Regimen.

[ 41 ]Genomic and expressional dynamics of ovarian cancer cell lines in PARPi treatment revealed mechanisms of acquired resistance

[ 42 ]UBE2C-mediated Autophagy Inhibition via Ubiquitination of SIRT1 Contributes to Endometrial Cancer Progression

[ 43 ]Targeted inhibition of the H3K27ac/OGT/O-GlcNAcylation axis to overcome gemcitabine-induced chemotherapy resistance in bladder cancer

[ 44 ]Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure

[ 45 ]Hsa_circ_0043278 functions as competitive endogenous RNA to enhance glioblastoma multiforme progression by sponging miR-638

[ 46 ]SMARCA4 deficiency in glioblastoma: Mitochondrial transfer from MSCs and the clinical dilemma in targeting the tumor microenvironment

[ 47 ]Hsp90 Inhibitor STA9090 induced VPS35 related extracellular vesicle release and metastasis in hepatocellular carcinoma

[ 48 ]The exon 12-containing LHX6 isoforms promote cervical cancer cell proliferation by regulating the MAPK signaling pathway

[ 49 ]DNA Methylation of the IL1R2 Gene Is Associated with Porcine Placental Development and Birth Weight

[ 50 ]Mitochondrial uncoupler BAM15 ameliorates liver lipid metabolism disorders by activating the AMPK pathway

[ 51 ]The radiosensitizing effects of a STAT3/HDAC dual-target inhibitor derived from isoalantolactone in solid tumor models

[ 52 ]The SP1-12LOX axis promotes chemoresistance and metastasis of ovarian cancer

[ 53 ]Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress

[ 54 ]HOXB8 enhances the proliferation and metastasis of colorectal cancer cells by promoting EMT via STAT3 activation

[ 55 ]Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling

[ 56 ]Identification of a new p53 responsive element in the promoter region of anillin

[ 57 ]Matrine improves skeletal muscle atrophy by inhibiting E3 ubiquitin ligases and activating the Akt/mTOR/FoxO3α signaling pathway in C2C12 myotubes and mice

[ 58 ]FNDC5 expression closely correlates with muscle fiber types in porcine longissimus dorsi muscle and regulates myosin heavy chains (MyHCs) mRNA expression in C2C12 cells

[ 59 ]Inhibition of TGF-β pathway improved the pluripotency of porcine pluripotent stem cells

[ 60 ]Functional mechanism and clinical implications of lncRNA NNT-AS1 in delayed fracture healing

[ 61 ]Targeting MUC1-C reverses the cisplatin resistance of esophageal squamous cell carcinoma in vitro and in vivo

[ 62 ]Depletion of rRNA Methyltranferase METTL5 Enhances Anti-Tumor Immune Response via Neoantigen Generated from Cryptic Translation

[ 63 ]Rapid and efficient in vivo angiogenesis directed by electro-assisted bioprinting of alginate/collagen microspheres with human umbilical vein endothelial cell coating layer