仙茅中新型氯酚苷类化合物及其对5α-还原酶的抑制活性研究
New chlorophenolic glycoside from Curculigo orchioides and their activities on 5α-reductase
Xue-Li Deng, Rui-Rong Zheng, Zhu-Zhen Han, Li-Hua Gu, Zheng-Tao Wang
Journal：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
IF：1.35
DOI：10.1080/10286020.2020.1731800
PMID：32131631
Published：2020-03-05
research field：环境基因组学分子进化结构生物学生物技术海洋微生物学
Abstract
Two new chlorophenolic glucosides curculigines P (1) and Q (2), together with seven known compounds (3–9), were isolated from the dried rhizomes of Curculigo orchioides. Their structures were determined by spectroscopic methods including 1 D, 2 D NMR and MS. All the isolated compounds were evaluated on 5α-reductase activity by a HaCaT-based bioassay. Compounds 1–9 showed varying degrees of inhibiting activity against 5α-reductase, while compound 1 indicated the most potent inhibitory effect.
本文使用的Yeasen产品
相关产品
产品应用
