Ramipril(HOE-498)是一种血管紧张素转化酶抑制剂。
|
英文别名 (English Synonym) |
Ramipril |
|
中文名称 (Chinese Name) |
雷米普利 |
|
靶点 (Target) |
ACE |
|
通路 (Pathway) |
Protease/Metabolic Enzyme |
|
CAS号 (CAS NO.) |
87333-19-5 |
|
分子式 (Formula) |
C23H32N2O5 |
|
分子量 (Molecular Weight) |
416.51 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Stevens BR, Phillips MI, Fernandez A. Ramipril inhibition of rabbit (Oryctolagus cuniculus) small intestinal brush border membrane angiotensin converting enzyme. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988,91(2):493-7. doi: 10.1016/0742-8413(88)90066-7. PMID: 2905962.[2]Kohlstedt K, Brandes RP, Müller-Esterl W, Busse R, Fleming I. Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells. Circ Res. 2004 Jan 9,94(1):60-7. doi: 10.1161/01.RES.0000107195.13573.E4. Epub 2003 Nov 13. PMID: 14615289.
