Crisaborole，又称克立硼罗，是PDE4选择性抑制剂，具有抗炎活性，是非激素类皮肤科外用药物，用于局部治疗轻度至中度特异性皮炎。

参考文献

[1] Nazarian R, Weinberg JM. AN-2728, a PDE4 inhibitor for the potential topical treatment of psoriasis and atopic dermatitis. Curr Opin Investig Drugs. 2009 Nov;10(11):1236-42.

[2] Ciaravino V, Coronado D, Lanphear C, et al. Post-transfer editing by a eukaryotic leucyl-tRNA synthetase resistant to the broad-spectrum drug AN2690. J Dermatol Sci. 2017 Aug;87(2):116-122. doi: 10.1016/j.jdermsci.2017.03.020(IF: 3.986).

-25~-15℃保存，有效期3年。