Fibroblast Growth Factor 18 (FGF-18) is a 20 kDa protein that plays an important role in skeletal development and bone homeostasis. Mature mouse FGF-18 shares 99% amino acid sequence identity with human and rat FGF-18. It is expressed in embryonic somites and the neural fold, adult lung, cerebellar and hippocampal neurons, hair follicle root sheath cells, and osteogenic mesenchymal cells. FGF-18 binds to FGF R2c, FGF R3c as well as the Golgi protein GLG1 and induces the proliferation of astrocytes and microglia, vascular endothelial cells, dermal fibroblasts, papilla cells, and keratinocytes. FGF-18 is required for normal skeletal development. It recruits osteoclasts and osteoblasts to the growth plate, promotes osteoclast formation and function, inhibits osteoblast differentiation, promotes skeletal vascularization, and induces chondrocyte hypertrophy and cartilage matrix formation.
高纯度、高活性、低内毒素、高批间一致性
-25 ~ -15℃保存,收到货之后有效期1年。 复溶后,无菌条件下,2~8℃保存,7天有效期。复溶后, 无菌条件下,-85 ~ -65℃保存,3个月有效期。
[97058ES]Human FGF-10 ELISA Kit
[91327ES]Recombinant Rat FGF-18 重组大鼠成纤维细胞生长因子-18
[91321ES]Recombinant Mouse FGF-17 重组小鼠成纤维细胞生长因子-17
[91320ES]Recombinant Mouse FGF-16 重组小鼠成纤维细胞生长因子-16
[91310ES]Recombinant Human FGF-17 重组人成纤维细胞生长因子-17
[91309ES]Recombinant Human FGF-16 重组人成纤维细胞生长因子-16
[91308ES]Recombinant Human FGF-13 重组人成纤维细胞生长因子-13
[91307ES]Recombinant Human FGF-12 重组人成纤维细胞生长因子-12
[91326ES]Recombinant Rat KGF-2/FGF-10 重组大鼠KGF-2/FGF-10
[91319ES]Recombinant Mouse KGF-2/FGF-10 重组小鼠KGF-2/FGF-10
[91311ES]Recombinant Human FGF-19 Protein,Flag Tag 重组人成纤维细胞生长因子-19
[91306ES]Recombinant Human FGF-10/KGF-2 Protein 重组人成纤维细胞生长因子-10