The human IL-2 protein, also known as interleukin-2, is an important cytokine that plays a vital role in regulating the immune system. It is produced by activated T cells and stimulates the proliferation and activation of various immune cells, such as T cells, B cells, and natural killer cells. IL-2 also promotes the development of immune memory and enhances the effectiveness of the immune response against infections and cancers. In addition, IL-2 has been used therapeutically in the treatment of certain diseases, such as cancer and autoimmune disorders, to boost the immune system.

 

性能参数

Synonyms	Interleukin-2; T-Cell Growth Factor; TCGF; Aldesleukin
Uniprot No.	P60568
Source	HEK293 cells-derived human IL-2 protein, Ala21-Thr153, with N-terminal his tag.
Molecular Weight	Approximately 17.35 kDa.
Purity	> 90% as determined by SDS-PAGE.
Biological Activity	Human IL-2R immobilized on CM5 chip can bind human IL-2, His tag, with an affinity constant of 3.84 x 10-7 M as determined in a SPR assay (Biacore 8K).
Endotoxin	< 1 EU per 1μg of the protein by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered concentrated solution in PBS.
Reconstitution	Centrifuge tubes before opening. Dissolve lyophilized protein with PBS. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

储存条件

The product should be stored at -25~-15℃ for 1 year from date of receipt.

2-7 days, 2 ~8 °C under sterile conditions after reconstitution.

3 months, -25~-15℃ under sterile conditions after reconstitution.

 

注意事项

1.Please operate with lab coats and disposable gloves, for your safety.

2.This product is for research use only.

 

产品数据

SDS-PAGE                                              SPR Data