Phloridzin
产品详情
FAQ
产品文档
已发表文献
产品介绍

Phloridzin是一种非选择性SGLT抑制剂;该化合物同时可抑制Na+/K+-ATP酶活性,属于二氢查耳酮类黄酮化合物。

产品性质
产品特色
英文别名 (English Synonym)Phloridzin
中文名称 (Chinese Name)根皮苷
靶点 (Target)SGLT
通路 (Pathway)Natural Products
CAS号 (CAS NO.)60-81-1
分子式 (Formula)C21H24O10
分子量 (Molecular Weight)436.41
纯度 (Purity)≥98%
溶解性 (Solubility)溶于DMSO


存储条件

-25~-15℃保存,有效期3年

COA
已发表文献

[1] Pajor AM, Randolph KM, Kerner SA, Smith CD. Inhibitor binding in the human renal low- and high-affinity Na+/glucose cotransporters. J Pharmacol Exp Ther. 2008 Mar;324(3):985-91. doi: 10.1124/jpet.107.129825. Epub 2007 Dec 6. PMID: 18063724.[2]Nakagawa A, Nakao M. Localization of the phlorizin site on Na, K-ATPase in red cell membranes. J Biochem. 1977 May;81(5):1511-5. PMID: 142763.[3]Chang WT, Huang WC, Liou CJ. Evaluation of the anti-inflammatory effects of phloretin and phlorizin in lipopolysaccharide-stimulated mouse macrophages. Food Chem. 2012 Sep 15;134(2):972-9. doi: 10.1016/j.foodchem.2012.03.002. Epub 2012 Mar 7. PMID: 23107715.[4]Katsuda Y, Sasase T, Tadaki H, Mera Y, Motohashi Y, Kemmochi Y, Toyoda K, Kakimoto K, Kume S, Ohta T. Contribution of hyperglycemia on diabetic complications in obese type 2 diabetic SDT fatty rats: effects of SGLT inhibitor phlorizin. Exp Anim. 2015;64(2):161-9. doi: 10.1538/expanim.14-0084. Epub 2015 Jan 22. PMID: 25736710; PMCID: PMC4427731.

购物车
客服
转染试用