Mesothelin is normally expressed on mesothelial cells in the pleura, pericardium, and peritoneum as well as in the developing and postnatal pancreas. It is upregulated in mesotheliomas and a range of carcinomas and adenomas. Mesothelin promotes tumor cell proliferation, migration, anchorage-independent growth, and tumor progression.

 

产品性质

Synonyms	MSLN; CAK1; Mesothelin; MPF; MPFSMRP; SMR
Uniprot No.	Q13421-2
Source	Recombinant FITC-Labeled Human MSLN/Mesothelin Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Glu296-Gly580
Molecular Weight	The protein has a predicted MW of 35.2 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Purity	> 95% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU per 1μg of the protein by the LAL method.
Formulation	Supplied as from 0.22 μm filtered solution in PBS (pH 7.4).

 

运输与保存方法

The products are shipped with ice pack and can be stored at -80℃ for 1 year.

Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.

 

注意事项

1.For your safety and health, please wear lab coats and disposable gloves for operation.

2.For research use only!