Product Description

 

The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane. In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein.

 

Product Properties

 

Synonyms	HBsAgadr; Hepatitis B virus surface antigen
Source	CHO derived HBsAgadr
Molecular Weight	Approximately 23.0-27.0 kDa on a reducing SDS-PAGE.
Tag	None
Physical Appearance	Sterile liquid.
Purity	> 95 % by HPLC analyses.
Biological Activity	The biological activity is determined by ELISA with anti-HBsAg antibodies.
Endotoxin	< 1.0 EU per 1μg of the protein by the LAL method.
Formulation	Sterile Filtered solution containing 20 mM PB,154 mM NaCl.
Concentration	240 μg/mL

 

Shipping and Storage

 

Do not freeze.

The products are shipped with ice pack and can be stored at 2℃ to 8℃ for 1 year.

3 months, 2 to 8℃ under sterile conditions after opening. 

 

Cautions

 

1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only.

 

HB20240926