Fibroblast growth factor-9, also called FGF-9, is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted human FGF-9 is a 205-207 aa protein that lacks the N-terminal 1-3 aa and shares 98% sequence identity with mouse, rat, equine, porcine and bovine FGF-9. In addition to FGF R3 (IIIb), FGF-9 binding to the IIIc splice forms of FGF R1, R2 and R3 are variably reported. FGF-9 is an autocrine/paracrine growth factor considered to be important for the growth and survival of motorneurons and prostate. Meanwhile, FGF9 is a potent mitogen and survival factor required for morphogenesis during embryonic development and numerous biological functions at adulthood. FGF9 have been shown to improve systolic function after myocardial infarction in a clinical trial. FGF9 promotes cardiac vascularization during embryonic development but is only weakly expressed in the adult heart.

高纯度、高活性、低内毒素、高批间一致性

                                      SDS-PAGE

5 ug/lane protein was resolved with SDS-PAGE under non-reducing (NR) and reducing (R) conditions and visualized by Coomassie Blue staining.

                                        Bioactivity

Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The EC50 for this effect is less than 0.5 ng/ml.

                                       ELISA

Immobilized FGF-9 Protein, Mouse at 5.0μg/mL (100μL/well) can bind Human FGF R2 (IIIb) protein, Fc Tag with EC50 of 20.82-36.17 ng/mL.

                                                                        类器官培养

小鼠肾类器官呈球形或椭球形，表面光滑，无明显破损或中心坏死。

-25 ~ -15℃保存，收到货之后有效期1年。
复溶后，无菌条件下，2~8℃保存，7天有效期。复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。