Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of RASSF1 in 293T lysates using RASSF1 antibody

Immunohistochemistry analysis of paraffin-embedded Human liver cancer using RASSF1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.