Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.
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别名 |
VDAC1; PORIN;PORIN-31-HL; |
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SwissProt ID |
P21796 |
|
基因ID |
7416 |
|
免疫原 |
A synthesized peptide derived from human VDAC1 |
|
缓冲液 |
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol |
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分子量 |
31kDa |
|
克隆类型 |
Polyclonal Antibody |
|
亚型 |
Rabbit IgG |
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宿主 |
Rabbit |
|
物种反应 |
Human,Mouse,Rabbit |
|
纯化方式 |
Affinity Chromatography |
|
细胞定位 |
细胞膜，膜筏，线粒体外膜，多通膜蛋白 |
|
研究领域 |
内分泌代谢 |
应用
稀释比 WB: 1/500-1/2000 IHC: 1/50-1/200
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Western blot analysis of Calreticulin expression in (1) HepG2 cell lysate; (2) Jurkat cell lysate. |
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Immunohistochemical analysis of paraffin-embedded human liver, using VDAC1 Antibody |
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Western blot analysis of VDAC1 expression in C2C12,THP-1,3T3,Jurakt and Hela cell lysates using VDAC1 antibody at 1/1 dilution.Predicted band size:31KDa.Observed band size:31KDa. |
冰袋运输，-20℃保存，1年有效期。
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